Pandorum Technologies Research Scientist Job For PhD Candidates
Founded in 2011 by academic entrepreneurs, Pandorum Technologies Pvt. Ltd. is a Bangalore based biotechnology company with focus on tissue engineering and regenerative medicine. With its distinct synergy of life science, engineering and clinical competences, the company designs and manufactures three dimensional functional human tissues; intended for medical research and therapeutics.
Pandorum Technologies is supported by the Biotechnology Industry Research Assistance Council, Department of Biotechnology, GoI. Pandorum’s labs are presently located in the Center for Cellular and Molecular Platforms, National Centre for Biological Sciences campus, Bengaluru, and in the Bangalore Bioinnovation Centre, Biotech Park, Electronics City Phase 1, Bengaluru.
Job Name – Senior Research Scientist
Location – Bengaluru, Karnataka, India On-site
About the job
Responsible for innovating and developing novel 3D organoid model and organoid-based assays for disease modelling and drug screening using medium to high throughput biomarker quantification and characterization.
Primary responsibilities:
- Ideate, plan and implement novel 3D culture methods to generate tissue-specific organoid disease models and their characterization and validation
- Identify challenges and opportunities in the field of human-relevant micro physiological systems (MPS) and organoid models for drug screening
- Understand and work on exploratory programs for inducing disease-relevant phenotypes (injury, inflammation and fibrosis), develop novel micro-fluidic-based organ-on chip culture and biomarker characterization
- Manage a team and collaborate across different teams
- Design study plans and outlines the experimental structure, assign project goals and timelines within the team
- Conduct laboratory studies, evaluate and troubleshoot efficiently
- Delegate and supervise the execution by the team members and interpret the data outputs from cell-based assays, ELISA, microscopy and transcriptomics
- Evaluate, develop, and apply diverse cutting-edge methods for quantification of bio-markers from immunofluorescence and histology readouts
- Provide expertise in state-of-the-art cell biology techniques and perform hands-on work in cell-based assays and drug discovery
- Implement best practices within the team and ensure proper documentation of data.
- Contribute to patent drafting, and grant writing and provide regular interim project updates to the senior management and stakeholders
Other responsibilities:
- Lead technical discussions with CROs and service providers for outsourcing samples and contribute to the implementation of new technologies
- Mentor and guide junior team members on research techniques and their professional development
- Develop efficient and productive work culture with scientists within the department, and other colleagues across R&D and non-R&D departments within the organization
- Support development of novel protocols, reports and SOPs, and data management
Qualifications:
- PhD with 4 to 6 years of Industry experience in isolation and culture of human primary cells, cell biology, assay and analytical development
- Prior experience with disease modelling and 3D culture is a plus
- Demonstrated knowledge of working with investigational drug compounds and drug discovery
- Experience in writing scientific articles, research proposals, and knowledge of intellectual property
- Expert knowledge of state-of-the-art principles and strong understanding of disease biology (inflammation and fibrosis)
- Hands-on experience in various assays like ELISA, Flow Cytometry, FACS, Microscopy and other relevant techniques
- Possess thorough knowledge of software like ImageJ, Graphpad PRISM
- Excellent communication and presentation skills.
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